DOTA-tris(tert-butyl ester) Novabiochem

DOTA-tris(tert-butyl ester) Novabiochem - Names and Identifiers

Name	TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD
Synonyms	DOTA-tris(t-Bu ester) DOTA-tris(tert-butyl ester) Novabiochem TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetate Tri-tert-butyl 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetate (4,7,10-Tris-tert-butoxycarbonylmethyl-1,4,7,10tetraaza-cyclododec-1-yl)-acetic acid Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetate DOTA-tris(tBu)ester Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetate DOTA-tris(tBu)ester 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, 1,4,7-tris(1,1-dimethylethyl) ester 2-[4,7,10-tris[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7,10-tetrazacyclododec-1-yl]acetic acid
CAS	137076-54-1
InChIKey	RVUXZXMKYMSWOM-UHFFFAOYSA-N

DOTA-tris(tert-butyl ester) Novabiochem - Physico-chemical Properties

Molecular Formula	C28H52N4O8
Molar Mass	572.73
Density	1.079
Melting Point	129-131℃
Boling Point	632.1±55.0 °C(Predicted)
Solubility	Aqueous Base (Slightly), Chloroform (Slightly), DMSO (Slightly),Methanol (Slight
Appearance	Form Solid, color Pale Beige
Color	Pale Beige
pKa	4.24±0.10(Predicted)
Storage Condition	Inert atmosphere,2-8°C
Use	Uses Tri-tert-butyl 1,4,7,10-tetraazacyclododecane -1,4,7,10-tetraacetic acid is an organic intermediate. It has been reported that tri-tert-butyl 1,4,7,10-tetraazacyclododecane -1,4,7,10-tetraacetic acid can be used to prepare peptide dendrimers. Peptide dendrimers are a new type of biomedical polymer materials developed in recent years. In addition to the characteristics of ordinary dendrimers, such as regularity, highly branched, high-density functional groups on the surface, and the scale is nanometer Level, a single molecular weight can be obtained through controllable preparation, and it also has the same spherical structure as protein, good biocompatibility, water solubility, protease hydrolysis resistance, biodegradability and other excellent properties.

DOTA-tris(tert-butyl ester) Novabiochem - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany	3
HS Code	29339900

DOTA-tris(tert-butyl ester) Novabiochem - Upstream Downstream Industry

Raw Materials	Potassium carbonate Triethylamine Bromoacetic acid Cyclen tert-Butyl bromoacetate
Downstream Products	DOTA-mono-NHS-tris(t-Bu ester)(B-270) 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, 1-(2,5-dioxo-1-pyrrolidinyl) ester

DOTA-tris(tert-butyl ester) Novabiochem - Nature

Solubility

Aqueous Base (Slightly), Chloroform (Slightly), DMSO (Slightly),Methanol (Slight

Last Update：2024-04-10 22:29:15

DOTA-tris(tert-butyl ester) Novabiochem - Reference Information

use

tri-tert-butyl 1,4,7,10-tetraazacyclodecane -1,4,7,10-tetraacetic acid is an organic intermediate, and reports show that tri-tert-butyl 1,4,7,10-tetraazacyclodecane -1,4,7,10-tetraacetic acid can be used to prepare peptide dendrimers.
Peptide dendrimers are a new type of biomedical polymer materials developed in recent years. In addition to the characteristics of ordinary dendrimers, such as regularity, high branching, and high-density functional groups on the surface. The scale is nanoscale, and a single molecular weight can be obtained through controllable preparation, at the same time, it also has the same spherical structure as protein, good biocompatibility, water solubility, protease hydrolysis resistance, biodegradability and other excellent properties.

Last Update：2024-04-09 21:01:54

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